MEDICINAL CHEMISTRY- III (Practical)


I Preparation of drugs and intermediates
1 Sulphanilamide
2 7-Hydroxy, 4-methyl coumarin
3 Chlorobutanol
4 Triphenyl imidazole
5 Tolbutamide
6 Hexamine

II Assay of drugs
1 Isonicotinic acid hydrazide
2 Chloroquine
3 Metronidazole
4 Dapsone
5 Chlorpheniramine maleate
6 Benzyl penicillin

III Preparation of medicinally important compounds or intermediates by Microwave
irradiation technique

IV Drawing structures and reactions using chem draw®

V Determination of physicochemical properties such as logP, clogP, MR, Molecular
weight, Hydrogen bond donors and acceptors for class of drugs course content
using drug design software Drug likeliness screening (Lipinskies RO5)
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