PHARMACEUTICS- I (Theory)



UNIT – I 

Historical background and development of profession of pharmacy: History
of profession of Pharmacy in India in relation to pharmacy education, industry
and organization, Pharmacy as a career, Pharmacopoeias: Introduction to IP, BP, USP and Extra Pharmacopoeia. 
 Dosage forms: Introduction to dosage forms, classification and definitions 
 Prescription: Definition, Parts of prescription, handling of Prescription and
Errors in prescription. 
Posology: Definition, Factors affecting posology. Pediatric dose calculations
based on age, body weight and body surface area. 

UNIT – II 

 Pharmaceutical calculations: Weights and measures – Imperial & Metric
system, Calculations involving percentage solutions, alligation, proof spirit and
isotonic solutions based on freezing point and molecular weight. 

Powders: Definition, classification, advantages and disadvantages,Simple &
compound powders – official preparations, dusting powders, effervescent,
efflorescent and hygroscopic powders, eutectic mixtures. Geometric dilutions. 
Liquid dosage forms: Advantages and disadvantages of liquid dosage forms.
Excipients used in formulation of liquid dosage forms. Solubility enhancement techniques

UNIT – III 

Monophasic liquids: Definitions and preparations of Gargles, Mouthwashes,
Throat Paint, Eardrops, Nasal drops, Enemas, Syrups, Elixirs, Liniments and
Lotions. 
Biphasic liquids
Suspensions: Definition, advantages and disadvantages, classifications,
Preparation of suspensions; Flocculated and Deflocculated suspension & stability
problems and methods to overcome. 
 Emulsions: Definition, classification, emulsifying agent, test for the identification
of type ofEmulsion, Methods of preparation & stability problems and methods to overcome. 

UNIT – IV

Suppositories: Definition, types, advantages and disadvantages, types of bases,
methods of preparations. Displacement value & its calculations, evaluation of
suppositories. 

Pharmaceutical incompatibilities: Definition, classification, physical, chemical
and therapeutic incompatibilities with examples.

UNIV – V

 Semisolid dosage forms: Definitions, classification, mechanisms and factors
influencing dermal penetration of drugs. Preparation of ointments, pastes, creams
and gels. Excipients used in semi solid dosage forms. Evaluation of semi solid
dosages forms
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