NOVEL DRUG DELIVERY SYSTEMS (Theory)

MATERIAL 👈👈 CLICK HERE

Unit-I 

Controlled drug delivery systems: Introduction, terminology/definitions and rationale, advantages, disadvantages, selection of drug candidates.Approaches to design controlled

release formulations based on diffusion, dissolution and ion exchange principles. Physicochemical and biological properties of drugs relevant to controlled release

formulations

Polymers: Introduction, classification, properties, advantages and application of

polymers in formulation of controlled release drug delivery systems.

Unit-II 

Microencapsulation: Definition, advantages and disadvantages, microspheres

/microcapsules, microparticles, methods of microencapsulation, applications

Mucosal Drug Delivery system: Introduction, Principles of bioadhesion /

mucoadhesion, concepts, advantages and disadvantages, transmucosal permeability and

formulation considerations of buccal delivery systems

Implantable Drug Delivery Systems:Introduction, advantages and disadvantages,

concept of implantsand osmotic pump

Unit-III 

Transdermal Drug Delivery Systems: Introduction, Permeation through skin, factors

affecting permeation, permeation enhancers, basic components of TDDS, formulation

approaches

Gastroretentive drug delivery systems: Introduction, advantages, disadvantages, approaches for GRDDS – Floating, high density systems, inflatable and gastroadhesive

systems and their applications

Nasopulmonary drug delivery system: Introduction to Nasal and Pulmonary routes of

drug delivery, Formulation of Inhalers (dry powder and metered dose), nasal sprays,

nebulizers

UNIT-IV

Targeted drug Delivery: Concepts and approaches advantages and disadvantages,

introduction to liposomes, niosomes, nanoparticles, monoclonal antibodies and their applications 

Unit-V 

Ocular Drug Delivery Systems: Introduction, intra ocular barriers and methods to

overcome –Preliminary study, ocular formulations and ocuserts

Intrauterine Drug Delivery Systems: Introduction, advantages and disadvantages,

development of intra uterine devices (IUDs) and applications