PHARMACOLOGY-I (Theory)

KD TRIPATHI PHARMACOLOGY MCQS

UNIT-I 

1. General Pharmacology   

a. Introduction to Pharmacology- Definition, historical landmarks and scope of pharmacology, 

nature and source of drugs, essential drugs concept and routes of  drug administration, 

Agonists, antagonists( competitive and non competitive), spare receptors, addiction, tolerance, dependence, tachyphylaxis, idiosyncrasy, allergy. 

b. Pharmacokinetics- Membrane transport, 

absorption, distribution, metabolism and excretion of drugs .

Enzyme induction, enzyme inhibition, kinetics of elimination

MCQs on 

• General pharmacological principles  part 1
• General pharmacological principles  part 2

UNIT-II

General Pharmacology

a. Pharmacodynamics- Principles and mechanisms of drug action. Receptor theories

and classification of receptors, regulation of receptors. drug receptors interactions

signal transduction mechanisms, G-protein–coupled receptors, ion channel receptor,

transmembrane enzyme linked receptors, transmembrane JAK-STAT binding

receptor and receptors that regulate transcription factors, dose response

relationship, therapeutic index, combined effects of drugs and factors modifying

drug action.

b. Adverse drug reactions.

c. Drug interactions (pharmacokinetic and pharmacodynamic)

d. Drug discovery and clinical evaluation of new drugs -Drug discovery phase, preclinical evaluation phase, clinical trial phase, phases of clinical trials and

pharmacovigilance.

MCQs on 

• General pharmacological principles  part 3
• General pharmacological principles  part 4

UNIT-III

2. Pharmacology of drugs acting on peripheral nervous system

a. Organization and function of ANS. 

b.Neurohumoral transmission,co-transmission and classification of neurotransmitters. 

c. Parasympathomimetics, Parasympatholytics, Sympathomimetics, sympatholytics.

d. Neuromuscular blocking agents and skeletal muscle relaxants (peripheral).

e. Local anesthetic agents.

f. Drugs used in myasthenia gravis and glaucoma

MCQs-

• Drugs Acting on Peripheral (Somatic) Nervous System part 1

• Drugs Acting on Peripheral (Somatic) Nervous System part 2

UNIT-IV  

3. Pharmacology of drugs acting on central nervous system

a. Neurohumoral transmission in the C.N.S.special emphasis on importance of various

neurotransmitters like with GABA, Glutamate, Glycine, serotonin, dopamine. 

b. General anesthetics and pre-anesthetics. 

c. Sedatives, hypnotics and centrally acting muscle relaxants.

d. Anti-epileptics

e. Alcohols and disulfiram

MCQs of CNS 

UNIT-V

3. Pharmacology of drugs acting on central nervous system

a. Psychopharmacological agents: Antipsychotics, antidepressants, anti-anxiety agents,

anti-manics and hallucinogens.

b. Drugs used in Parkinsons disease and Alzheimer’s disease.

c. CNS stimulants and nootropics.

d. Opioid analgesics and antagonists

e. Drug addiction, drug abuse, tolerance and dependence.