MATERIAL 👈👈 CLICK HERE
Unit-I
Controlled drug delivery systems: Introduction, terminology/definitions and rationale, advantages, disadvantages, selection of drug candidates.Approaches to design controlled
release formulations based on diffusion, dissolution and ion exchange principles. Physicochemical and biological properties of drugs relevant to controlled release
formulations
Polymers: Introduction, classification, properties, advantages and application of
polymers in formulation of controlled release drug delivery systems.
Unit-II
Microencapsulation: Definition, advantages and disadvantages, microspheres
/microcapsules, microparticles, methods of microencapsulation, applications
Mucosal Drug Delivery system: Introduction, Principles of bioadhesion /
mucoadhesion, concepts, advantages and disadvantages, transmucosal permeability and
formulation considerations of buccal delivery systems
Implantable Drug Delivery Systems:Introduction, advantages and disadvantages,
concept of implantsand osmotic pump
Unit-III
Transdermal Drug Delivery Systems: Introduction, Permeation through skin, factors
affecting permeation, permeation enhancers, basic components of TDDS, formulation
approaches
Gastroretentive drug delivery systems: Introduction, advantages, disadvantages, approaches for GRDDS – Floating, high density systems, inflatable and gastroadhesive
systems and their applications
Nasopulmonary drug delivery system: Introduction to Nasal and Pulmonary routes of
drug delivery, Formulation of Inhalers (dry powder and metered dose), nasal sprays,
nebulizers
UNIT-IV
Targeted drug Delivery: Concepts and approaches advantages and disadvantages,
introduction to liposomes, niosomes, nanoparticles, monoclonal antibodies and their
applications
Unit-V
Ocular Drug Delivery Systems: Introduction, intra ocular barriers and methods to
overcome –Preliminary study, ocular formulations and ocuserts
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