Part 1
1.1 `Essential drugs’ are:
A. Life saving drugs
B. Drugs that meet the priority health care needs of the population
C. Drugs that must be present in the emergency
bag of a doctor
D. Drugs that are listed in the pharmacopoia of a
country
1.2 An 'orphan drug' is:
A. A very cheap drug
B. A drug which has no therapeutic use
C. A drug needed for treatment or prevention of a rare disease
D. A drug which acts on Orphanin receptors
1.3 Drug administered through the following route is most likely to be subjected to first-pass metabolism:
A. Oral
B. Sublingual
C. Subcutaneous
D. Rectal
1.4 Transdermal drug delivery systems offer the following advantages except:
A. They produce high peak plasma concentration of the drug
B. They produce smooth and nonfluctuating plasma concentration of the drug
C. They minimise interindividual variations in the achieved plasma drug concentration
D. They avoid hepatic first-pass metabolism of the drug
1.5 In addition to slow intravenous infusion, which of the following routes of administration allows for titration of
the dose of a drug with the response:
A. Sublingual
B. Transdermal
C. Inhalational
D. Nasal insufflation
1.6 Which of the following drugs is administered by intranasal spray/application for systemic action:
A. Phenylephrine
B. Desmopressin
C. Azelastine
D. Beclomethasone dipropionate
1.7 Compared to subcutaneous injection, the intramus- cular injection of drugs:
A. Is more painful
B. Produces faster response
C. Is unsuitable for depot preparations
D. Carries greater risk of anaphylactic reaction
1.8 Select the route of administration which carries the highest risk of adversely affecting vital functions:
A. Intra arterial injection
B. Intrathecal injection
C. Intravenous injection
D. Intramuscular injection
1.1 B 1.2 C 1.3 A 1.4 A 1.5 C 1.6 B 1.7 B 1.8 C