MCQS- PHYSICAL PHARMACEUTICS 1 | MCQS- PHYSICAL PHARMACEUTICS 2

1. Following are used for particle size analysis
P. Coulter counter 
Q. BET N2 adsorption
R. XRPD S. HIAC counter
(a) Q and S 
(b) P and S
(c) Q, R and S 
(d) R and S

2. Which instrument is used for the determination of shear rate/shear stress?
(a) Ultrasonifier 
(b) Rotational viscometer
(c) Accela cota 
(d) Chilsonator

3. Colloid particle have …………… type of rheology.
(a) Newtonian flow
(b) Pseudoplastic flow
(c) Non-Newtonian flow
(d) Dilatant

4. Wetting agent has …………… HLB value.
(a) 1 to 3 
(b) 3 to 6
(c) 7 to 9 
(d) 8 to 18

5. Carr’s compressibility index gives an idea about
(a) Flow property of powders
(b) Cohesiveness of powders
(c) Both
(d) None

6. Following is not a derived property of powder:
(a) Surface area 
(b) Particle size
(c) Bulk density 
(d) None

7. Following is not the method for determining the surface area of particles:
(a) Adsorption method
(b) Mercury displacement method
(c) BET method
(d) Air permeability method

8. Following is related to the air permeability method:
(a) Kozeny Carman equation
(b) BET equation
(c) Kelvin equation
(d) Stocks’ equation

9. Kelvin equation is related to the
(a) Particle size analysis
(b) Pore size analysis
(c) Surface area analysis
(d) Sedimentation

10. Following is not used as a measure of flow property of
powder:
(a) Compressibility index
(b) Hausner’s ratio
(c) Angle of repose
(d) Bulk density

11. ____________ is a zwitterionic surfactant.
(a) SLS
(b) Lecithin
(c) Tween
(d) Benzalkonium chloride

12. Following gel shows a thixotropic behavior
(a) Bentonite 
(b) Starch
(c) Pectin 
(d) Silica

13. Sorbitan esters, used as nonionic surfactants, are
(a) Tweens 
(b) Spans
(c) Polawaxes 
(d) Poloxalkols

14. A surfactant X forming poor/no dispersion in water at room temperature will be having an HLB value ______
(a) < 5 
(b) 7–10
(c) 12–15 
(d) 15

15. Phase inversion temperature is also called ________
(a) Fusion temperature
(b) Collapse temp.
(c) Transition temperature
(d) HLB temperature

16. First-order half-life is equal to
(a) 1/k 
(b) k
(c) 0.693/k 
(d) 2k+1

17. Which of the following property is the derived property of powder?
(a) Size distribution
(b) Surface area of powder
(c) Porosity
(d) None of above

18. The slope of rheogram of a plastic flow is called ____.
(a) Mobility 
(b) Fluidity
(c) Yield value 
(d) Yield stress

19. In case of colloids, particles in red gold sol increase in size, the colour of dispersion will become _____.
(a) Red 
(b) Blue
(c) Green 
(d) Yellow

20. Air permeability method is used to determine the ___________ of powder.
(a) Volume 
(b) Density
(c) Weight
(d) Specific surface area

21. Red blood cells are ________.
(a) Molecular dispersion
(b) Colloidal dispersion
(c) Coarse dispersion
(d) None of above

22. Which of the following method is used to determine the surface area of particles?
(a) Sedimentation 
(b) Hydrometer
(c) Coulter counter 
(d) Adsorption method

23. The reciprocal of bulk density is ________.
(a) Porosity 
(b) Bulkiness
(c) Both of above 
(d) None of above

24. Ordinarily, interfacial tensions are _________ than surface tension.
(a) Greater 
(b) Lesser
(c) Same 
(d) Cannot be determined

25. Kinematic viscosity is the absolute viscosity divided by the ________ at specific temperature.
(a) Weight of liquid 
(b) Density of liquid
(c) Unit times
(d) None of above

26. What is the formula to find surface area of a spherical particle?
(a) π d³/6
(b) π d²
(c) π d 
(d) π d³

27. Mac Michael viscometer is a type of ___________ viscometer.
(a) Capillary viscometer
(b) Falling sphere viscometer
(c) Cup and bob viscometer
(d) Cone and plate viscometer

28. Shearing stress is _____.
(a) Force required to bring about flow
(b) Force per unit area required to bring about flow
(c) Force per unit time required to bring about flow
(d) None of above

29. Water is __________ fluid
(a) Newtonian 
(b) Non-newtonian
(c) Both (a) and (b) 
(d) None of above

30. Suspension follows _____kinetics.
(a) Zero-order 
(b) Apparent zero-order
(c) First-order 
(d) Second-order

31. Higher the HLB value of surfactant, more __________ it is.
(a) Hydrophilc 
(b) Lipophilic
(c) Amphoteric 
(d) None of above

32. When one of the reactants is present in such great excess then its concentration may be considered constant or nearly so, the reaction is said to be________
(a) Zero order 
(b) Apparent zero order
(c) First order 
(d) Second order

33. Bingham bodies show which type of flow?
(a) Newtonian flow 
(b) Plastic flow
(c) Pseudoplastic 
(d) Dilatant.

34. The instrument used for measuring the volume of particles is
(a) Hydrometer
(b) Balance
(c) Anderson pipette
(d) Coulter counter

35. The particle size range of colloidal dispersion is _____.
(a) 1 nm to 1 µm 
(b) 1 nm to 0.5 µm
(c) 1 nm to 100 nm 
(d) Greater than 100 nm

36. Inorganic particles such as gold and silver dispersed in water form ___________?
(a) Lyophilic 
(b) Lyophobic
(c) Amphiphilic 
(d) None of above

37. The Du-Nouy ring method (Du-Nouy tensiometer) determines _______
(a) Surface tension
(b) Interfacial tension
(c) Both (a) and (b)
(d) None of above

38. ________-shaped particles have the minimum surface area per unit volume.
(a) Square 
(b) Rectangular
(c) Spherical 
(d) Oblong

39. Roto viscometer is a type of _______ viscometer.
(a) Couette type
(b) Cup and bob
(c) Searle-type cup and bob
(d) None

40. Bulkiness (specific bulk volume) ____________ with a decrease in particle size.
(a) Increases
(b) Decreases
(c) Cannot be determined
(d) None of above

41. With increasing departure from spherical, the flowability ___________.
(a) Increases
(b) Decreases
(c) Can either increase or decrease
(d) None of above

42. A sample of a powder with true density of 3 g/cm³ and weighing 100 g was found to have bulk volume of 80.33 cm³ when placed in a 100-ml graduated cylinder. Calculate the porosity.
(a) 0.41 
(b) 0.58
(c) 0.31 
(d) 0.25

43. Thixotropy phenomenon can be applied to __________ system.
(a) Shear thinning system
(b) Shear thickening system
(c) Both of above
(d) None of above.

44. Faraday Tyndall effect in colloids occurs due to __________?
(a) Reflection of light by colloidal particles
(b) Brownian motion of colloidal particles
(c) Scattering of light by colloidal particles
(d) Diffusion of particles

45. Which of the following surfactant also possess anti-bacterial activity?
(a) Glyceryl monostearate
(b) Quaternary ammonium compounds
(c) Sodium oleate
(d) Sodium lauryl sulphate

46. A solvent sheath is formed around the particles of dispersed phase in __________ type of colloidal system.
(a) Lyophilic 
(b) Lyophobic
(c) Amphiphilic 
(d) None of above

47. Pseudoplastic flow is typically exhibited by
(a) Emulsion 
(b) Polymer solution
(c) Suspension 
(d) Ointment

48. Which of the following method is used to obtain surface tension?
(a) X-ray diffraction
(b) Karl Fischer method
(c) Capillary rise method
(d) Sedimentation method

49. If the Carr’s index of a powder is 10% then the type of powder flow is
(a) Poor 
(b) Excellent
(c) Very poor 
(d) Good

50. One of the following ingredients improves the flow property of granules in
(a) Glidant 
(b) Emollient
(c) Lubricant 
(d) Surfactant


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