1. α-D-glucose and β-D-glucose both are
(a) Keto-aldo pairs
(b) Anomers
(c) Epimers
(d) Stereoisomers
2. Compounds that have the same structural formula but different spatial configuration are called
(a) Epimers
(b) Anomers
(c) Stereoisomers
(d) Optical isomers
3. One of the following is a reducing sugar:
(a) Isomaltose (b) Sucrose
(c) Trehalose (d) None of the above
4. An L-isomer of monosaccharide formed in human body during uronic acid pathway is
(a) L-Xylulose (b) L-Erythrose
(c) L-Ribulose (d) L-Fructose
5. Which of the following is an epimeric pair?
(a) Glucose and fructose
(b) Lactose and maltose
(c) Galactose and mannose
(d) Glucose and mannose
6. One of the following is an enzyme required for glycolysis pathway:
(a) Pyruvate carboxylase
(b) Pyruvate kinase
(c) Fructose-6-phosphatase
(d) Phosphokinase
7. Glucose tolerance is decreased in one of the following disease:
(a) Diabetes insipidus
(b) Addison’s disease
(c) Hypo pituitarisme
(d) Diabetes mellitus
8. In carbohydrate metabolism all of the following hormones is involved except:
(a) Glucagon (b) ACTH
(c) Vasopressin (d) Insulin
9. For converting glucose to glycogen in liver an essential component is
(a) UTP
(b) GTP
(c) GLU-1
(d) Lactic acid
10. Phenylalanine is the precursor of
(a) Histamine
(b) Dopamine
(c) Tyrosine
(d) Thyroxin
11. One of the following amino acids contains special group pyrrolidine:
(a) Proline
(b) Tyrosine
(c) Tryptophan
(d) Phenylalanine
12. The cyclic hemiacetal formation in D-Glucose involves bond formation between
(a) C-1 and C-4
(b) C-1 and C-5
(c) C-2 and C-5
(d) C-1 and C-2
13. Cori cycle is
(a) Reuse of glucose
(b) Synthesis of glucose
(c) Uptake of glucose
(d) Both (a) and (b)
14. Invert sugar is
(a) Galactose
(b) Mannose
(c) Fructose
(d) Hydrolytic product of sucrose
15. Generally all proteins contain
(a) More than 50 amino acids
(b) Different amino acids less than50
(c) Only a few amino acids
(d) 300 amino acids occurring in nature
16. An example of sulphur-containing amino acid is
(a) 3-Amino butanoic acid
(b) 2-Amino-3-methylbutanoic acid
(c) 2-Amino-3-thiobutanoic acid
(d) 2-Amino-3-mercaptopropanoic acid
17. At isoelectric pH, a mixture of amino acids in solution would be predominantly:
(a) Zwitter ions
(b) Nonpolar molecules
(c) Hydrophilic
(d) Positive and monovalent
18. Dispensible amino acids
(a) Can not be synthesized by the body
(b) May be synthesized in the body to meet biological needs.
(c) Have no role in the metabolism
(d) May be synthesized in the body in diseased states
19. The technique for purification of proteins that can be made specific for a given protein is
(a) Gel filtration chromatography
(b) Thin layer chromatography
(c) Affinity chromatography
(d) Electrophoresis
20. Amino acid tryptophan could be considered as precursor of
(a) Meltonin
(b) Thyroid hormones
(c) Methionine
(d) Phenylephrine
21. The enzyme dopamine β-hydroxylase which catalyses
conversion of dopamine to norepinephrine requires
(a) Vitamin C
(b) Vitamin A
(c) Vitamin K
(d) Vitamin B1
22. Pulses are deficient in______ amino acid.
(a) Lysine
(b) Tyrosine
(c) Methionine
(d) Crystine
23. _________, a water-soluble vitamin is absent in eggs.
(a) Biotin
(b) Niacin
(c) Ribofalvin
(d) Ascrobic acid
24. Primary structure of a protein is formed by
(a) Disulphide bonds
(b) Hydrogen bonds
(c) Peptide bonds
(d) Amine bonds
25. Semi-essential amino acid is
(a) Valine
(b) Histidine
(c) Asparagine
(d) Serine
26. Alanine can be synthesized from
(a) Pyruvate and glutamate
(b) Glycine and α-ketoglutarate
(c) Pyruvate and α ketoglutarate
(d) Asparate and pyruvate
27. Glycine can be synthesized from
(a) Serine (b) Threonine
(c) Betaine (d) All of these
28. Non-protein amino acids are
(a) Ornithine
(b) β-alanine
(c) γ-amino butyric acid
(d) All of these
29. Allergic reactions are mediated by
(a) IgE (b) IgG
(c) IgA (d) IgD
30. A Zwitter ion is a
(a) Molecule containing negative ion
(b) Molecule containing positive ion
(c) Molecule containing positive and negative ionic group
(d) None of these
31. Synthesis of calcitonin takes place in
(a) Parathyroid glands
(b) Anterior pituitary glands
(c) Thyroid gland
(d) Adrenal medulla
32. The basic amino acid is
(a) Lysine (b) Proline
(c) Leucine (d) Tyrosine
33. For adrenaline synthesis the precursor amino acid is
(a) Alanine
(b) Proline
(c) Phenylalanine
(d) Cystine
34. Amino acids are soluble in
(a) Ammonia (b) Water
(c) Chloroform (d) Benzene
35. Optically active compounds are capable of
(a) Rotating plane of polarized light
(b) Emitted the light radiation
(c) Showing same chemical properties
(d) Different chemical reaction
36. SGOT level in an adult is
(a) 15–45 units/dl
(b) 10–50 units/dl
(c) 5–15 units/dl
(d) 5–40 units/dl
37. Zymogen is
(a) An inactivated enzyme
(b) An activated enzyme
(c) An intracellular enzyme
(d) An extracellular enzyme
38. Xanthoproteic test is positive for
(a) Sulphur amino acids
(b) Indole ring containing amino acids
(c) Aromatic amino acids
(d) α-amino acids
39. Michaelis–Menton equation is used to explain the effect of substrate concentration on
(a) Carbohydrate
(b) Protein
(c) Lipid
(d) Enzyme
40. Low plasma level of tryptophan and other neutral amino acid leads to the disorder is known as
(a) Maple syrup disease
(b) Wilson’s disease
(c) Hartnup’s disease
(d) Wolman’s disease
41. A dietary deficiency in the quantity of protein results in
(a) Alkaptonuria
(b) Marasmus
(c) Richner–Hanhart syndrome
(d) Kwashiorkar
42. The normal range of total serum bilirubin is
(a) 0.2–1.2 mg/100 ml
(b) 1.5–1.8 mg/100 ml
(c) 2.0–4.0 mg/100 ml
(d) Above 7.0 mg/100 ml
43. A test to evaluate the detoxifying function of liver is
(a) Serum albumin: globulin ratio
(b) Galactose tolerance test
(c) Hippuric acid test
(d) Prothrombin time
44. Fat-soluble vitamins have properties like
(a) Stored in liver
(b) One or more propene units
(c) Soluble in alcohol
(d) All these
45. Precursor of vitamin A, β-carotene is oxidatively cleaved by
(a) Hydroxylase
(b) Oxygenase
(c) β-Carotene dioxygenase
(d) Reductase
46. Carr–Price reaction is used to detect
(a) Vitamin E (b) Vitamin B12
(c) Aspartic acid (d) Vitamin A
47. Deficiency of vitamin D causes
(a) Tuberculosis of bone
(b) Ricket and osteomalacia
(c) Pellagra
(d) Beri-beri
48. Vitamin D absorption is increased in
(a) Contents of diet
(b) Alkaline pH of intestine
(c) Neutral pH of stomach
(d) Acid pH of intestine
49. One international unit (IU) of vitamin D is defined as the biological activity of
(a) 0.025 µg of ergosterol
(b) 0.025 µg of 7-dehydrocholecalciferol
(c) 0.025 µg of cholecalciferol
(d) 0.025 µg of ergocalciferol
50. One of the following vitamins is synthesized by bacteria in the intestine
(a) Vitamin A (b) Vitamin K
(c) Vitamin D (d) Vitamin E
51. Due to the riboflavin deficiency _________ is caused.
(a) Pellagra (b) Mental deterioration
(c) Cheilosis (d) Dermatitis
52. Vitamin B6 deficiency may occur during tuberculosis therapy with
(a) Isoniazid
(b) Rifampicin
(c) Sulpha drugs
(d) Thamibutole
53. Xanthurenic Acid Index’ is a reliable criterion for the deficiency of vitamin
(a) Pantothenic acid
(b) Thiamin
(c) Pyridoxal
(d) Riboflavin
54. For determination of amino acid sequence of a protein ____________ is used.
(a) Ninhydrin reagent
(b) Biuret reagent
(c) Milons reagen
(d) Sanger reagent
55. The deficiency of folate causes
(a) Pernicious anaemia
(b) Megaloblastic anaemia
(c) Macrocytic anaemia
(d) Hemolytic anaemia
56. Folic acid contains
(a) Pteridine
(b) p-Amino benzoic acid
(c) Glutamic acid
(d) All of these
57. Vitamin A is synthesized from
(a) γ-Carotene
(b) β-Carotene
(c) α-Carotene
(d) All of these
58. The molecule of vitamin A1 contains
(a) β-Carotene ring
(b) β-Lonone ring
(c) Naphthalene ring
(d) α-Lactone ring
59. A chemical name of vitamin K3 is
(a) Phylloquinone
(b) Menadione
(c) Menaquinone
(d) Napthoquinone
60. The rhodopsin contain non-protein part is
(a) Retinal
(b) Retinol
(c) Carotene
(d) Retinoic acid
61. Vitamin K regulates the synthesis of blood clotting factors:
(a) VII
(b) IX
(c) X
(d) All of these
62. Vitamin which has anti-oxidant properties is
(a) Vitamin A (b) Vitamin C
(c) Vitamin D (d) Vitamin E
63. Severe deficiency of _____causes xerophthalmia.
(a) Vitamin D (b) Vitamin B2
(c) Vitamin B6 (d) Vitamin A
64. Antisterility vitamin is
(a) Biotin
(b) Riboflavin
(c) Vitamin E
(d) Vitamin K
65. Thymine is characterized as a
(a) Water-soluble vitamin
(b) Fat-soluble vitamin
(c) Purine base
(d) Pyrimidine base
66. All of following is antagonist for folic acid except
(a) Aminopterin (b) Trimethoprim
(c) Sulfonamides (d) Isoniazid
67. Calcitriol is
(a) 1,25-dihydroxy cholecalciferol
(b) 1-hydroxy cholecalciferol
(c) 25,26-dihydroxy cholecalciferol
(d) 25-hydroxy cholecalciferol
68. Which of the following vitamin act as a respiratory catalyst?
(a) Riboflavin
(b) Pyridoxine
(c) Niacin
(d) Vitamin E
69. Vitamin B12 contains _____metal.
(a) Copper (b) Iron
(c) Cobalt (d) Lead
70. Nonsteroidal antiinflammatory drugs, such as aspirin act by inhibiting the activity of the enzyme:
(a) Lipoxygenase
(b) Cyclooxygenase
(c) Phospholipase A2
(d) Lipoprotein lipase
71. Holoenzyme is
(a) Functional unit of enzyme
(b) Made of apoenzyme
(c) Coenzyme
(d) All of these
72. Enzymes, which are produced in inactive form in the living cells, are called
(a) Co-enzyme
(b) Apoenzymes
(c) Proenzymes
(d) Isozymes
73. Vitamin B2 is the precursor for
(a) Co enzyme pyridoxal phosphate
(b) Co enzyme thiamine pyrophosphate
(c) Co enzyme FMN
(d) Co enzyme NADP
74. In reversible non-competitive enzyme activity inhibition
(a) Vmax value is increased
(b) Km value is increased
(c) Km value is decreased
(d) Concentration of active enzyme is decreased
75. The specificity of the enzyme is mostly dependent on
(a) Glucose
(b) Pyruvate
(c) Xanthurenic acid
(d) Thiamine pyro phosphate
76. The specificity of the enzyme is mostly dependant on
(a) Co-enzyme
(b) Apoenzymes
(c) Proenzymes
(d) Isozymes
77. How many number of net ATP generated during oxidation of one molecule of palmitate?
(a) 14
(b) 21
(c) 129
(d) 96
78. Factors affecting enzyme activity is
(a) Temperature
(b) pH
(c) Concentration
(d) All of these
79. Glucose absorption is promoted by
(a) Vitamin A
(b) Vitamin E
(c) Ascorbic acid
(d) Thiamin
80. Zellweger syndrome occurs due to the:
(a) Absence of peroxisomes
(b) Deficiency of vitamin B12
(c) Deficiency of acyl CoA dehydrogenase
(d) Overproduction of ketone
81. Ketosis is generally associated with the disease:
(a) Nephritis
(b) Diabetes Insipidus
(c) Edema
(d) Diabetes mellitus
82. Conversion of HMG-CoA to the mevalonate by the reduction is catalysed by
(a) HMG-CoA reductase
(b) HMG-CoA synthetase
(c) Thiolase
(d) Mevalonate kinase
83. One of the following amino acids is used as an antibiotic
(a) Thyroxine
(b) Ornithine
(c) Homoserine
(d) Azaserine
84. Sulfur-containing B-complex vitamin is
(a) Biotin
(b) Niacin
(c) Pyridoxine
(d) Riboflavin
85. One of the following vitamins is known as pellagra preventive factor of Goldberg:
(a) Biotin
(b) Niacin
(c) Riboflavin
(d) Pyridoxine
86. Adenylate cyclase is activated by
(a) Insulin
(b) Vitamin K
(c) Prostaglandin E1
(d) Glucagon
87. Coenzyme A is derived from the vitamin:
(a) Niacin
(b) Pantothenic acid
(c) Pyridoxine
(d) Biotin
88. The Michaelis–Menten constant, Km is defined as
(a) Substrate concentration to produce half maximal velocity in an enzyme catalysed reaction
(b) Dependent on the enzyme concentration
(c) Substrate concentration to produce half minimal velocity in an enzyme catalysed reaction
(d) Numerically equal to ½Vmax
89. ‘Lock and key’ theory was proposed by
(a) Koshland
(b) Emil Fischer
(c) Mehler
(d) Sanger
90. Allosteric inhibitor of hexokinase enzyme is
(a) Glucose-6-phosphate
(b) Palmitate
(c) AMP
(d) ATP
91. The non-protein, organic and low molecular weight substance, bound to an enzyme and essential for the
activity of enzyme is known as
(a) Holoenzyme
(b) Coenzyme
(c) Isoenzyme
(d) Apoenzyme
92. When in enzyme inhibition Km value is unchanged and Vmax is value is decreased then it known as
(a) Allostreric inhibition
(b) Reversible non-competitive inhibition
(c) Reversible competitive inhibition
(d) Irreversible inhibition
93. If two monosaccharides differ from each other in their configuration around single specific carbon atom other than anomeric carbon they are known as
(a) Epimers
(b) Enediols
(c) Stereoisomers
(d) Optical isomers
94. Chemically Barfoed’s reagent is
(a) Copper acetate and glacial acetic acid
(b) Resorcinol in hydrochloric acid
(c) Copper sulphate in sulphuric acid
(d) Phenylhydrazine in hydrochloric acid
95. Poisoning of morphine causes
(a) Metabolic acidosis
(b) Respiratory alkalosis
(c) Metabolic alkalosis
(d) Respiratory acidosis
96. Which enzyme hydrolyses starch?
(a) Invertase
(b) Amylase
(c) Sucrase
(d) Maltase
97. One of the following amino acid is nonessential
(a) Arginine
(b) Valine
(c) Glutamate
(d) Lysine
98. The oxidation of glucose to pyruvate and lactate is known as
(a) Glycolysis
(b) Gluconeogenesis
(c) Glycogenesis
(d) Glycogenolysis
99. Citric acid cycle is also known as
(a) Uronic acid cycle
(b) Reductive pathway of carbohydrate
(c) Krebs cycle
(d) Synthesis of glucose from non-carbohydrate precursor
100. Embden–Meyerhof pathway is also known as
(a) Hexose monophosphate shunt
(b) Oxidative pathway of carbohydrate
(c) Krebs cycle
(d) Glycolysis
Part 2 👈👈